BIRMINGHAM, UK (June 12, 2014) – The coefficient of friction (CoF) of 1-DAY ACUVUE® TruEye® Brand Contact Lenses (narafilcon A) and of ACUVUE® OASYS® Brand Contact Lenses (senofilcon A) were found to be comparable to that of the human cornea, according to new research presented at the 2014 British Contact Lens Association Clinical Conference (BCLA). The data demonstrated no statistically significant difference between CoF of human corneal tissue and 1-DAY ACUVUE® TruEye® Brand and ACUVUE® OASYS® Brand Contact Lenses at study baseline or following 18 hours of simulated wear.
“These results suggest that the lens surface of these two contact lens brands is as lubricious as the human cornea,” says Tawnya Wilson, O.D., Principal Research Optometrist at Johnson & Johnson Vision Care, Inc. “This is important because coefficient of friction has previously been shown to be one factor highly correlated with contact lens comfort1,2. 1-DAY ACUVUE® TruEye® and ACUVUE® OASYS® seem to mimic corneal properties that may help address end-of-day comfort for many of our patients.”
About the Study
CoF testing was conducted on 1-DAY ACUVUE® TruEye® and ACUVUE® OASYS® Brand Contact Lenses directly out of the package (0-hour) utilising a micro-tribometer in a tear-like fluid with phosphate buffer saline (300-310 mOsm/kg). The applied normal force varied between 0.25 and 4.0 mN with a measured stroke length of 1.0mm at normal blink speed of 0.1mm per second. A mucin-coated glass disc was used as counter surface mimicking the inner eyelid. A simulated aged cycling (18-hour) of the contact lenses was also completed using the same measurement methodology. The results were compared to CoF of human corneal tissue recently published using the same methodology3, and statistical analysis was conducted using an analysis of variance (ANOVA).
This study found that the 1-DAY ACUVUE® TruEye® LS mean (SD) 0-hour CoF was 0.0080 (0.001140) (N=13) and 0.0098 (0.002055) at 18-hour (N=4). ACUVUE® OASYS® LS mean (SD) 0-hour CoF was 0.0104 (0.001300) (N=10) and 0.0116 (0.001300) at 18-hour (N=10). The CoF of human corneal tissue is 0.0153 (0.002974).
Dunnett’s t-tests on least squares means from the ANOVA model revealed no statistical differences at 0.05 significance level between corneal tissue and each study contact lens at 0-hour and 18-hour: 1-DAY ACUVUE® TruEye® (0-hour) vs. cornea -0.007 (StdErr 0.003) (p=0.067); 1-DAY ACUVUE® TruEye® (18-hour) vs. cornea -0.006 (StdErr 0.004) (p=0.27); ACUVUE® OASYS® (0-hour) vs. cornea -0.005 (StdErr 0.003) (p=0.281); and, ACUVUE® OASYS® (18-hour) vs. cornea -0.004 (StdErr 0.003) (p=0.479).
Source: Wilson, T, Aeschlimann, R, Tosatti, S, Toubouti, Y, Kakkassery, J, Osborn-Lorenz, K, “Comparison of Frictional Behavior of Human Corneal Tissue and Silicone Hydrogel Contact Lenses.” Poster presented June 7, 2014 at the 2014 British Contact Lens Association Clinical Conference
ACUVUE® Brand Contact Lenses are indicated for vision correction. As with any contact lens, eye problems, including corneal ulcers, can develop. Some wearers may experience mild irritation, itching or discomfort. Lenses should not be prescribed if patients have any eye infection, or experience eye discomfort, excessive tearing, vision changes, redness or other eye problems. Consult the package insert for complete information. Complete information is also available from VISTAKON® Division of Johnson & Johnson Vision Care, Inc., by calling 1-800-843-2020 or by visiting www.ACUVUEProfessional.com.
COEFFICIENT OF FRICTION OF 1-DAY ACUVUE® TruEye® AND ACUVUE® OASYS® COMPARABLE TO THE HUMAN CORNEA, STUDY SHOWS/2
Johnson & Johnson Vision Care, Inc.
Johnson & Johnson Vision Care, Inc. is committed to creating life-long solutions to vision care needs. Since the ACUVUE® Brand made its debut in 1987 as the world’s first disposable soft contact lens, the company has repeatedly brought innovative, quality, and scientific advancements to the industry. Headquartered in Jacksonville, Florida, the company has some 3,000 employees worldwide. For additional information, visit www.jnjvc.com.
ACUVUE®, 1-DAY ACUVUE® TruEye® and ACUVUE® OASYS® are trademarks of Johnson & Johnson Vision Care, Inc.
References:
- Brennan N. Coles C. Supportive Data Linking Coefficient of Friction and Comfort. Paper: BCLA, Manchester, UK, June 6-9, 2013.
- Brennan N. Coles C. Contact Lens-Based Correlates of Soft Lens Wearing Comfort. Optom Vis Sci 2009;86:E-abstract 90957.
- Wilson, T, Aeschlimann, R, Tosatti, S, Toubouti, Y, Kakkassery, J, Osborn-Lorenz, K, “Coefficient of Friction of Human Cornea Tissue.” Poster presented October 26, 2013 at The American Academy of Optometry 2013 meeting.